Diabetes

In the year 2003 the Center for Disease Control published that an estimated 18.2 million Americans have diabetes and approximately 20 million more have pre-diabetes Type II Diabetes Mellitus is one of the most common diseases among Americans over the age of 60 even though it is preventable in a large majority of cases. While it is currently an incurable disease, it is fortunately one of the most easily managed and controlled diseases that we know.

Doctors and scientists have know for quite some time that with proper diet and exercise, a person can easily control their blood glucose levels and reduce their risk for complications. Hypoxico is glad to announce the use of hypoxic therapy as a complimentary and extremely effective method for managing and controlling diabetes.

Through the combination of a customized IHT program, proper diet and nutritional maintenance as well as light exercise, Type II diabetes and in some case Type I Diabetes may be almost completely eliminated. While the need to monitor the disease will remain, the possibility of life threatening complications as a result of the disease may be almost completely eradicated.

Hypoxic therapy works to combat Diabetes in a similar fashion to exercise. Many of the benefits of exercise come from the creation of a hypoxic state within the body. While normoxic exercise may only bring the body’s blood oxygen saturation (Sa02) to around 95%, hypoxic therapy can more efficiently reduce this value to 80-85% and lower. This distinction provides hypoxic therapy with a unique advantage over exercise in the promotion of:

     • Glucose uptake into cells
     • Weight-loss
     • Decreased blood pressure
     • Reduced cholesterol levels.

The mechanism for these effects is as follows. An acute state of hypoxia within the cells leads to insufficient oxygen for energy production. In turn, the cell increases production of non-insulin dependent glucose transporters, allowing more glucose to be taken into cells and transformed into energy. This reaction is vital for diabetics who either don’t produce enough insulin or can’t use it to promote glucose uptake into cells.

Both exercise and hypoxic therapy can cause this switch to anaerobic metabolism, stimulating fat burning and weight-loss. However, there is another mechanism related to the mitochondria and unique to hypoxic therapy that also promotes weight-loss (see weight-loss section for details). The virtually non-existent effort requirement of hypoxic therapy in promoting glucose uptake and weight-loss makes it a superior treatment for diabetes, a disease which is strongly associated with obesity and lack of physical activity.

Sufferers of Type II Diabetes Mellitus can expect the following benefits from the use of hypoxic therapy:

     • controlled blood glucose levels
     • increased fat burning
     • decreased blood pressure
     • stress relief
     • reduced probability of disease-related health complications (eg. Renal failure,        retinopathy etc.)

Research

This study suggests that hypoxia is capable of stimulating the glucose transport effecter system not only in lean and obese human skeletal muscle, but also in diabetic human skeletal muscle.

Hypoxico stimulates glucose transport in insulin-resistant human skeletal muscle. Azevado et al. 1995

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This study from the medical journal Diabetes supports that hypoxia enhances glucose transport activity through an up regulation of the glucose transporter known as GLUT1. The graph from the article displays the “dose” dependent increased expression of the glucose transporter as a result of exposure to hypoxia.

Hypoxia up regulates glucose transport activity through an Adenosine-mediated increase of GLUT1 expression in retinal capillary endothelial cells. Takagi, King and Aiello. 1998

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This study notes the benefits of traditional exercise training for individuals with diabetes.

Henriksen, EJ. Exercise Effects of Muscle Insulin Signaling and Action Invited Review: Effects of acute exercise and exercise training on insulin resistance. Journal of Applied Physiology 93: 788-796, 2002

THE STATEMENTS CONTAINED HERIN HAVE NOT BEEN EVALUATED BY THE FDA AND ARE NOT INTENDED TO DIAGNOSE, TREAT OR CURE ANY DISEASE OR AILMENT